Recombinant Full Length Human CNP Protein, C-Flag-tagged

• Cat.No.: CNP-1747HFL
• Product Overview: Recombinant Full Length Human CNP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Predicted to enable 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity. Involved in substantia nigra development. Located in several cellular components, including extracellular space; microtubule; and plasma membrane. Implicated in hypomyelinating leukodystrophy 20; multiple sclerosis; and schizophrenia. Biomarker of alcoholic liver cirrhosis; multiple sclerosis; and restless legs syndrome.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.4 kDa
• AA Sequence: MNRGFSRKSHTFLPKIFFRKMSSSG AKDKPELQFPFLQDEDTVATLLECK TLFILRGLPGSGKSTLARVI VDKYRDGTKMVSADAYKITPGARGA FSEEYKRLDEDLAAYCRRRDIRILV LDDTNHERERLEQLFEMADQ YQYQVVLVEPKTAWRLDCAQLKEKN QWQLSADDLKKLKPGLEKDFLPLYF GWFLTKKSSETLRKAGQVFL EELGNHKAFKKELRQFVPGDEPREK MDLVTYFGKRPPGVLHCTTKFCDYG KAPGAEEYAQQDVLKKSYSK AFTLTISALFVTPKTTGARVELSEQ QLQLWPSDVDKLSPTDNLPRGSRAH ITLGCAADVEAVQTGLDLLE ILRQEKGGSRGEEVGELSRGKLYSL GNGRWMLTLAKNMEVRAIFTGYYGK GKPVPTQGSRKGGALQSCTI
  ITRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: CNP 2',3'-cyclic nucleotide 3' phosphodiesterase [ Homo sapiens (human) ]
• Official Symbol: CNP
• Synonyms: CNP1; HLD20
• Gene ID: 1267
• mRNA Refseq: NM_033133.5
• Protein Refseq: NP_149124.3
• MIM: 123830
• UniProt ID: P09543