Recombinant Full Length Human COL6A2 Protein, C-Flag-tagged

• Cat.No.: COL6A2-1544HFL
• Product Overview: Recombinant Full Length Human COL6A2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 95.3 kDa
• AA Sequence: MLQGTCSVLLLWGILGAIQAQQQEV ISPDTTERNNNCPEKTDCPIHVYFV LDTSESVTMQSPTDILLFHM KQFVPQFISQLQNEFYLDQVALSWR YGGLHFSDQVEVFSPPGSDRASFIK NLQGISSFRRGTFTDCALAN MTEQIRQDRSKGTVHFAVVITDGHV TGSPCGGIKLQAERAREEGIRLFAV APNQNLKEQGLRDIASTPHE LYRNDYATMLPDSTEINQDTINRII KVMKHEAYGECYKVSCLEIPGPSGP KGYRGQKGAKGNMGEPGEPG QKGRQGDPGIEGPIGFPGPKGVPGF KGEKGEFGADGRKGAPGLAGKNGTD GQKGKLGRIGPPGCKGDPGN RGPDGYPGEAGSPGERGDQGGKGDP GRPGRRGPPGEIGAKGSKGYQGNNG APGSPGVKGAKGGPGPRGPK GEPGRRGDPGTKGSPGSDGPKGEKG DPGPEGPRGLAGEVGNKGAKGDRGL PGPRGPQGALGEPGKQGSRG DPGDAGPRGDSGQPGPKGDPGRPGF SYPGPRGAPGEKGEPGPRGPEGGRG DFGLKGEPGRKGEKGEPADP GPPGEPGPRGPRGVPGPEGEPGPPG DPGLTECDVMTYVRETCGCCDCEKR CGALDVVFVIDSSESIGYTN FTLEKNFVINVVNRLGAIAKDPKSE TGTRVGVVQYSHEGTFEAIQLDDEH IDSLSSFKEAVKNLEWIAGG TWTPSALKFAYDRLIKESRRQKTRV FAVVITDGRHDPRDDDLNLRALCDR DVTVTAIGIGDMFHEKHESE NLYSIACDKPQQVRNMTLFSDLVAE KFIDDMEDVLCPDPQIVCPDLPCQT DAPWPGGEPPVTFLRTEEGP DATFPRTIPLIQQLLNATELTQDPA AYSQLVAVLVYTAERAKFATGVERQ DWMELFIDTFKLVHRDIVGD
  PETALALCSGPTRTRRLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein
• Protein Pathways: ECM-receptor interaction, Focal adhesion

Gene Information

• Gene Name: COL6A2 collagen type VI alpha 2 chain [ Homo sapiens (human) ]
• Official Symbol: COL6A2
• Synonyms: UCMD1; BTHLM1; PP3610
• Gene ID: 1292
• mRNA Refseq: NM_058174.3
• Protein Refseq: NP_478054.2
• MIM: 120240
• UniProt ID: P12110