Recombinant Full Length Human COP1 Protein, C-Flag-tagged
Cat.No. : | COP1-893HFL |
Product Overview : | Recombinant Full Length Human COP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Enables ubiquitin protein ligase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Part of Cul4A-RING E3 ubiquitin ligase complex. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 80.3 kDa |
AA Sequence : | MSGSRQAGSGSAGTSPGSSAASSVT SASSSLSSSPSPPSVAVSAAALVSG GVAQAAGSGGLGGPVRPVLV APAVSGSGGGAVSTGLSRHSCAARP SAGVGGSSSSLGSGSRKRPLLAPLC NGLINSYEDKSNDFVCPICF DMIEEAYMTKCGHSFCYKCIHQSLE DNNRCPKCNYVVDNIDHLYPNFLVN ELILKQKQRFEEKRFKLDHS VSSTNGHRWQIFQDWLGTDQDNLDL ANVNLMLELLVQKKKQLEAESHAAQ LQILMEFLKVARRNKREQLE QIQKELSVLEEDIKRVEEMSGLYSP VSEDSTVPQFEAPSPSHSSIIDSTE YSQPPGFSGSSQTKKQPWYN STLASRRKRLTAHFEDLEQCYFSTR MSRISDDSRTASQLDEFQECLSKFT RYNSVRPLATLSYASDLYNG SSIVSSIEFDRDCDYFAIAGVTKKI KVYEYDTVIQDAVDIHYPENEMTCN SKISCISWSSYHKNLLASSD YEGTVILWDGFTGQRSKVYQEHEKR CWSVDFNLMDPKLLASGSDDAKVKL WSTNLDNSVASIEAKANVCC VKFSPSSRYHLAFGCADHCVHYYDL RNTKQPIMVFKGHRKAVSYAKFVSG EEIVSASTDSQLKLWNVGKP YCLRSFKGHINEKNFVGLASNGDYI ACGSENNSLYLYYKGLSKTLLTFKF DTVKSVLDKDRKEDDTNEFV SAVCWRALPDGESNVLIAANSQGTI KVLELVTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | p53 signaling pathway, Ubiquitin mediated proteolysis |
Gene Name : | COP1 COP1 E3 ubiquitin ligase [ Homo sapiens (human) ] |
Official Symbol : | COP1 |
Synonyms : | FAP78; RFWD2; CFAP78; RNF200 |
Gene ID : | 64326 |
mRNA Refseq : | NM_022457.7 |
Protein Refseq : | NP_071902.2 |
MIM : | 608067 |
UniProt ID : | Q8NHY2 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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