Recombinant Full Length Human CRADD Protein, C-Flag-tagged
Cat.No. : | CRADD-1196HFL |
Product Overview : | Recombinant Full Length Human CRADD Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 22.6 kDa |
AA Sequence : | MEARDKQVLRSLRLELGAEVLVEGL VLQYLYQEGILTENHIQEINAQTTG LRKTMLLLDILPSRGPKAFD TFLDSLQEFPWVREKLKKAREEAMT DLPAGDRLTGIPSHILNSSPSDRQI NQLAQRLGPEWEPMVLSLGL SQTDIYRCKANHPHNVQSQVVEAFI RWRQRFGKQATFQSLHNGLRAVEVD PSLLLHMLETRTRPLEQKLISEEDL AANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | CRADD CASP2 and RIPK1 domain containing adaptor with death domain [ Homo sapiens (human) ] |
Official Symbol : | CRADD |
Synonyms : | MRT34; RAIDD |
Gene ID : | 8738 |
mRNA Refseq : | NM_003805.5 |
Protein Refseq : | NP_003796.1 |
MIM : | 603454 |
UniProt ID : | P78560 |
Products Types
◆ Recombinant Protein | ||
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CRADD-656H | Recombinant Human CRADD Protein, His (Fc)-Avi-tagged | +Inquiry |
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CRADD-840R | Recombinant Rhesus Macaque CRADD Protein, His (Fc)-Avi-tagged | +Inquiry |
Cradd-2304M | Recombinant Mouse Cradd Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
CRADD-7294HCL | Recombinant Human CRADD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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