Recombinant Full Length Human CRLF1 Protein, GST-tagged

• Cat.No.: CRLF1-96HF
• Product Overview: Recombinant Human CRLF1 encoding Human CRLF1 full-length ORF ( NP_004741.1, 1 aa - 422 aa),fused with GST-tag at N-terminal, was expressed in Wheat germ.

Specification

• Description: This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 72.7 kDa
• AA Sequence: MPAGRRGPAA QSARRPPPLL PLLLLLCVLG APRAGSGAHT AVISPQDPTL LIGSSLLATC SVHGDPPGAT AEGLYWTLNG RRLPPELSRV LNASTLALAL ANLNGSRQRS GDNLVCHARD GSILAGSCLY VGLPPEKPVN ISCWSKNMKD LTCRWTPGAH GETFLHTNYS LKYKLRWYGQ DNTCEEYHTV GPHSCHIPKD LALFTPYEIW VEATNRLGSA RSDVLTLDIL DVVTTDPPPD VHVSRVGGLE DQLSVRWVSP PALKDFLFQA KYQIRYRVED SVDWKVVDDV SNQTSCRLAG LKPGTVYFVQ VRCNPFGIYG SKKAGIWSEW SHPTAASTPR SERPGPGGGA CEPRGGEPSS GPVRRELKQF LGWLKKHAYC SNLSFRLYDQ WRAWMQKSHK TRNQDEGILP SGRRGTARGP AR
• Applications: WB; ELISA
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH8.0 in the elution buffer.

Gene Information

• Gene Name: CRLF1 cytokine receptor-like factor 1 [ Homo sapiens ]
• Official Symbol: CRLF1
• Synonyms: CRLF1; cytokine receptor-like factor 1; CISS; CISS1; CLF; CLF 1; cold induced sweating syndrome; cytokine-like factor 1; class I cytokine receptor; cytokine type 1 receptor CRLP-1; NR6; CLF-1; zcytor5
• Gene ID: 9244
• mRNA Refseq: NM_004750
• Protein Refseq: NP_004741
• MIM: 604237
• UniProt ID: O75462