Recombinant Full Length Human CYP21A2 Protein, GST-tagged
Cat.No. : | CYP21A2-2324HF |
Product Overview : | Human CYP21A2 full-length ORF (BAG37212.1, 1 a.a. - 495 a.a.) recombinant protein with GST tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 80.85 kDa |
Protein Length : | 495 amino acids |
AA Sequence : | MLLLGLLLLLPLLAGARLLWNWWKL RSLHLPPLAPGFLHLLQPDLPIYLL GLTQKFGPIYRLHLGLQDVVVLNSK RTIEEAMVKKWADFAGRPEPLTYKL VSRNYPDLSLGDYSLLWKAHKKLTR SALLLGIRDSMEPVVEQLTQEFCER MRAQPGTPVAIEEEFSLLTCSIICY LTFGDKIKDDNLMPAYYKCIQEVLK TWSHWSIQIVDVIPFLRFFPNPGLR RLKQAIEKRDHIVEMQLRQHKESLV AGQWRDMMDYMLQGVAQPSMEEGSG QLLEGHVHMAAVDLLIGGTETTANT LSWAVVFLLHHPEIQQRLQEELDHE LGPGASSSRVPYKDRARLPLLNATI AEVLRLRPVVPLALPHRTTRPSSIS GYDIPEGTVIIPNLQGAHLDETVWE RPHEFWPDRFLEPGKNSRALAFGCG ARVCLGEPLARLELFVVLTRLLQAF TLLPSGDALPSLQPLPHCSVILKMQ PFQVRLQPRGMGAHSPGQSQ |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 [ Homo sapiens ] |
Official Symbol : | CYP21A2 |
Synonyms : | CYP21A2; cytochrome P450, family 21, subfamily A, polypeptide 2; CYP21, CYP21B, cytochrome P450, subfamily XXIA (steroid 21 hydroxylase, congenital adrenal hyperplasia), polypeptide 2; steroid 21-hydroxylase; CA21H; CAH1; CPS1; P450c21B; Steroid 21 monooxygenase; 21-OHase; cytochrome P450 21; cytochrome P450 XXI; cytochrome P450-C21B; steroid 21-monooxygenase; cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2; CYP21; CYP21B; MGC150536; MGC150537; |
Gene ID : | 1589 |
mRNA Refseq : | NM_000500 |
Protein Refseq : | NP_000491 |
MIM : | 613815 |
UniProt ID : | P08686 |
Products Types
◆ Recombinant Protein | ||
CYP21A2-447H | Recombinant Human CYP21A2 Protein (1-494 aa), His-tagged | +Inquiry |
CYP21A2-964R | Recombinant Rhesus Macaque CYP21A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP21A2-699H | Recombinant Human CYP21A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP21A2-2249H | Recombinant Human CYP21A2 Protein, GST-tagged | +Inquiry |
CYP21A2-1180H | Recombinant Human CYP21A2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CYP21A2-7123HCL | Recombinant Human CYP21A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket