Recombinant Full Length Human DCT Protein, C-Flag-tagged

• Cat.No.: DCT-401HFL
• Product Overview: Recombinant Full Length Human DCT Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Predicted to enable dopachrome isomerase activity. Involved in response to blue light. Located in intracellular membrane-bounded organelle and plasma membrane. Implicated in oculocutaneous albinism.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 59 kDa
• AA Sequence: MSPLWWGFLLSCLGCKILPGAQGQF PRVCMTVDSLVNKECCPRLGAESAN VCGSQQGRGQCTEVRADTRP WSGPYILRNQDDRELWPRKFFHRTC KCTGNFAGYNCGDCKFGWTGPNCER KKPPVIRQNIHSLSPQEREQ FLGALDLAKKRVHPDYVITTQHWLG LLGPNGTQPQFANCSVYDFFVWLHY YSVRDTLLGPGRPYRAIDFS HQGPAFVTWHRYHLLCLERDLQRLI GNESFALPYWNFATGRNECDVCTDQ LFGAARPDDPTLISRNSRFS SWETVCDSLDDYNHLVTLCNGTYEG LLRRNQMGRNSMKLPTLKDIRDCLS LQKFDNPPFFQNSTFSFRNA LEGFDKADGTLDSQVMSLHNLVHSF LNGTNALPHSAANDPIFVVLHSFTD AIFDEWMKRFNPPADAWPQE LAPIGHNRMYNMVPFFPPVTNEELF LTSDQLGYSYAIDLPVSVEETPGWP TTLLVVMGTLVALVGLFVLL
  AFLQYRRLRKGYTPLMETHLSSKRY TEEATRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane
• Protein Pathways: Melanogenesis, Metabolic pathways, Tyrosine metabolism

Gene Information

• Gene Name: DCT dopachrome tautomerase [ Homo sapiens (human) ]
• Official Symbol: DCT
• Synonyms: TRP-2; TYRP2
• Gene ID: 1638
• mRNA Refseq: NM_001922.5
• Protein Refseq: NP_001913.2
• MIM: 191275
• UniProt ID: P40126