Recombinant Full Length Human DIABLO Protein, GST-tagged
Cat.No. : | DIABLO-2557HF |
Product Overview : | Human DIABLO full-length ORF (BAG50903.1, 1 a.a. - 186 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 47.6 kDa |
Protein Length : | 186 amino acids |
AA Sequence : | MKSDFYFQKSEPHSLSSEALMRRAV SLVTDSTSTFLSQTTYALIEAITEY TKAVYTLTSLYRQYTSLLGKMNSEE EDEVWQVIIGARAEMTSKHQEYLKL ETTWMTAVGLSEMAAEAAYQTGADQ ASITARNHIQLVKLQVEEVHQLSRK AETKLAEAQIEELRQKTQEEGEERA ESEQEAYLRED |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DIABLO diablo, IAP-binding mitochondrial protein [ Homo sapiens ] |
Official Symbol : | DIABLO |
Synonyms : | DIABLO; diablo, IAP-binding mitochondrial protein; diablo homolog, mitochondrial; DFNA64; DIABLO S; FLJ10537; FLJ25049; second mitochondria derived activator of caspase; SMAC; 0610041G12Rik; mitochondrial Smac protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; SMAC3; DIABLO-S; |
Gene ID : | 56616 |
mRNA Refseq : | NM_019887 |
Protein Refseq : | NP_063940 |
MIM : | 605219 |
UniProt ID : | Q9NR28 |
Products Types
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◆ Lysates | ||
DIABLO-6927HCL | Recombinant Human DIABLO 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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