Recombinant Full Length Human DNASE1L3 Protein, GST-tagged

• Cat.No.: DNASE1L3-1004HF
• Product Overview: Recombinant human full-length DNASE1L3 (NP_004935.1, 1 a.a. - 305 a.a.) was expressed in wheat germ with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0.
• Molecular Mass: 61.9 kDa
• Protein Length: 305 amino acids
• AA Sequence: MSRELAPLLL LLLSIHSALA MRICSFNVRS FGESKQEDKN AMDVIVKVIK RCDIILVMEI KDSNNRICPI LMEKLNRNSR RGITYNYVIS SRLGRNTYKE QYAFLYKEKL VSVKRSYHYH DYQDGDADVF SREPFVVWFQ SPHTAVKDFV IIPLHTTPET SVKEIDELVE VYTDVKHRWK AENFIFMGDF NAGCSYVPKK AWKNIRLRTD PRFVWLIGDQ EDTTVKKSTN CAYDRIVLRG QEIVSSVVPK SNSVFDFQKA YKLTEEEALD VSDHFPVEFK LQSSRAFTNS KKSVTLRKKT KSKRS
• Storage: Store at -80 centigrade.

Gene Information

• Gene Name: DNASE1L3 deoxyribonuclease 1 like 3 [ Homo sapiens (human) ]
• Official Symbol: DNASE1L3
• Synonyms: DHP2; DNAS1L3; LSD
• Gene ID: 1776
• mRNA Refseq: NM_004944.2
• Protein Refseq: NP_004935.1
• MIM: 602244
• UniProt ID: Q13609

Reviews

01/30/2023

The proteins accepted were of very high purity and were put into experiments with satisfactory results.

04/01/2022

Fast and timely shipment helped me to get satisfactory experimental results in short time.

07/21/2021

Excellent after-sales service, solving many experimental problems.

Q&As

What biological processes are DNASE1L3 involved in?

DNASE1L3 plays an important role in cell apoptosis and cell necrosis.

What does DNASE1L3 have to do with NET?

DNASE1L3 interacts with NET.

What diseases has DNASE1L3 been linked to studies of?

DNASE1L3 has been associated with the study of diseases such as hepatocellular carcinoma, gastric adenocarcinoma and colon cancer.

How does DNASE1L3 affect the development of hepatocellular carcinoma?

DNASE1L3 inhibits hepatocellular carcinoma progression by delaying cell cycle progression and attenuating glycolysis in hepatocellular carcinoma.