Recombinant Full Length Human ELAVL1 Protein, GST-tagged

• Cat.No.: ELAVL1-76HFL
• Product Overview: Recombinant Full Length Human ELAVL1 Protein(170-518 aa), fused with GST tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: GST
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH.
• Protein Length: 1-326 aa
• AA Sequence: MSNGYEDHMAEDCRGDIGRTNLIVN YLPQNMTQDELRSLFSSIGEVESAK LIRDKVAGHSLGYGFVNYVTAKDAE RAINTLNGLRLQSKTIKVSYARPSS EVIKDANLYISGLPRTMTQKDVEDM FSRFGRIINSRVLVDQTTGLSRGVA FIRFDKRSEAEEAITSFNGHKPPGS SEPITVKFAANPNQNKNVALLSQLY HSPARRFGGPVHHQAQRFRFSPMGV DHMSGLSGVNVPGNASSGWCIFIYN LGQDADEGILWQMFGPFGAVTNVKV IRDFNTNKCKGFGFVTMTNYEEAAM AIASLNGYRLGDKILQVSFKTNKSH K
• Purity: 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) [ Homo sapiens ]
• Official Symbol: ELAVL1
• Synonyms: ELAVL1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); HUR; ELAV-like protein 1; embryonic lethal; abnormal vision; drosophila; homolog like 1; Hu antigen R; Hua; HuR; MelG; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1; ELAV1
• Gene ID: 1994
• mRNA Refseq: NM_001419
• Protein Refseq: NP_001410
• MIM: 603466
• UniProt ID: Q15717

Reviews

12/19/2022

It is very pure and can be used with confidence.

07/20/2021

In enzymatic experiments, ELAVL1 was found to have high catalytic efficiency.

06/11/2020

In immunological experiments, it was found that ELAVL1 had good antigenicity and could induce target immune response.

Q&As

Is relationship between the ELAVL1 gene and the immune system?

Studies have shown that the ELAVL1 gene may be involved in the regulation of the immune system, especially in the inflammatory response.

What is the localization of the ELAVL1 gene in cells?

The protein encoded by the ELAVL1 gene is mainly located in the cytoplasm and nucleus.

What is the change in the expression level of ELAVL1 gene in tumors?

In some tumors, the expression level of ELAVL1 gene may be increased or decreased, which is related to the occurrence and progression of tumors.

What is the effect of ELAVL1 gene on apoptosis?

This gene may play an important role in the process of apoptosis, but its specific mechanism of action still needs further research.

How is the ELAVL1 gene involved in the differentiation of nerve cells?

ELAVL1 is involved in the differentiation of nerve cells by binding to and stabilizing neuronal cell-specific microRNAs.

In which tissues and organs is the ELAVL1 gene expressed?

This gene isexpressed in many tissues and organs, including the brain, heart, liver, muscles, etc.