| Description : |
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Molecular Mass : |
105.270kDa inclusive of tags |
| Protein Length : |
720 amino acids |
| AA Sequence : |
MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQ TAAEGDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLS RLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQE ELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKAS QKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPW NFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPC SFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDL HKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKI SYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQA SALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTS APAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED EPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQKKRERL DGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFME SVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGVSTLST |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
