Recombinant Full Length Human FGF19 Protein, C-Flag-tagged

• Cat.No.: FGF19-857HFL
• Product Overview: Recombinant Full Length Human FGF19 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 21.6 kDa
• AA Sequence: MRSGCVVVHVWILAGLWLAVAGRPL AFSDAGPHVHYGWGDPIRLRHLYTS GPHGLSSCFLRIRADGVVDC ARGQSAHSLLEIKAVALRTVAIKGV HSVRYLCMGADGKMQGLLQYSEEDC AFEEEIRPDGYNVYRSEKHR LPVSLSSAKQRQLYKNRGFLPLSHF LPMLPMVPEEPEDLRGHLESDMFSS PLETDSMDPFGLVTGLEAVR
  SPSFEKTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Gene Information

• Gene Name: FGF19 fibroblast growth factor 19 [ Homo sapiens (human) ]
• Official Symbol: FGF19
• Synonyms: fibroblast growth factor 19
• Gene ID: 9965
• mRNA Refseq: NM_005117.3
• Protein Refseq: NP_005108.1
• MIM: 603891
• UniProt ID: O95750