Recombinant Full Length Human FOXP3 Protein, C-Flag-tagged
Cat.No. : | FOXP3-1306HFL |
Product Overview : | Recombinant Full Length Human FOXP3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 47.1 kDa |
AA Sequence : | MPNPRPGKPSAPSLALGPSPGASPS WRAAPKASDLLGARGPGGTFQGRDL RGGAHASSSSLNPMPPSQLQ LPTLPLVMVAPSGARLGPLPHLQAL LQDRPHFMHQLSTVDAHARTPVLQV HPLESPAMISLTPPTTATGV FSLKARPGLPPGINVASLEWVSREP ALLCTFPNPSAPRKDSTLSAVPQSS YPLLANGVCKWPGCEKVFEE PEDFLKHCQADHLLDEKGRAQCLLQ REMVQSLEQQLVLEKEKLSAMQAHL AGKMALTKASSVASSDKGSC CIVAAGSQGPVVPAWSGPREAPDSL FAVRRHLWGSHGNSTFPEFLHNMDY FKFHNMRPPFTYATLIRWAI LEAPEKQRTLNEIYHWFTRMFAFFR NHPATWKNAIRHNLSLHKCFVRVES EKGAVWTVDELEFRKKRSQR PSRCSNPTPGPTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Transcription Factors |
Gene Name : | FOXP3 forkhead box P3 [ Homo sapiens (human) ] |
Official Symbol : | FOXP3 |
Synonyms : | JM2; AIID; IPEX; PIDX; XPID; DIETER |
Gene ID : | 50943 |
mRNA Refseq : | NM_014009.4 |
Protein Refseq : | NP_054728.2 |
MIM : | 300292 |
UniProt ID : | Q9BZS1 |
Products Types
◆ Recombinant Protein | ||
FOXP3-938H | Recombinant Human FOXP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
FOXP3-1568R | Recombinant Rhesus Macaque FOXP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Foxp3-3079M | Recombinant Mouse Foxp3 Protein, Myc/DDK-tagged | +Inquiry |
FOXP3-1216H | Recombinant Human FOXP3 Protein, His-tagged | +Inquiry |
Foxp3-1919M | Recombinant Mouse Foxp3 protein, His & GST-tagged | +Inquiry |
◆ Lysates | ||
FOXP3-6145HCL | Recombinant Human FOXP3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, elevated or decreased levels of FOXP3 expression can serve as a biomarker for various diseases, including autoimmune conditions and certain cancers.
Yes, the expression of FOXP3 in tumor-infiltrating lymphocytes is studied as a potential prognostic marker in various cancers, with higher levels often associated with a better prognosis.
FOXP3 is crucial for immune tolerance in transplant recipients. Enhancing Treg function, possibly through manipulating FOXP3, is a focus for transplant research to prevent rejection.
FOXP3 is studied in cancer to understand its role in suppressing anti-tumor immune responses. Manipulating Tregs or targeting FOXP3 may be explored for cancer immunotherapy.
FOXP3 helps regulate immune responses, including those involved in allergies. Dysfunction in FOXP3 or Tregs may contribute to allergic disorders.
Customer Reviews (3)
Write a reviewIts purity and integrity are of the highest standard, ensuring reliable and reproducible results in my research.
The FOXP3 protein offered by the manufacturer is of exceptional quality and is expected to perfectly meet my experimental needs.
The manufacturer's commitment to providing excellent technical support is commendable, as their dedicated team possesses the expertise to solve any issue or query that may arise during my experiments.
Ask a Question for All FOXP3 Products
Required fields are marked with *
My Review for All FOXP3 Products
Required fields are marked with *
Inquiry Basket