Recombinant Full Length Human GABARAP Protein, GST-tagged
Cat.No. : | GABARAP-5148HF |
Product Overview : | Human GABARAP full-length ORF ( NP_009209.1, 1 a.a. - 117 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 40.3 kDa |
Protein Length : | 117 amino acids |
AA Sequence : | MKFVYKEEHPFEKRRSEGEKIRKKY PDRVPVIVEKAPKARIGDLDKKKYL VPSDLTVGQFYFLIRKRIHLRAEDA LFFFVNNVIPPTSATMGQLYQEHHE EDFFLYIAYSDESVYGL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GABARAP GABA(A) receptor-associated protein [ Homo sapiens ] |
Official Symbol : | GABARAP |
Synonyms : | GABARAP; GABA(A) receptor-associated protein; gamma-aminobutyric acid receptor-associated protein; ATG8A; MM46; GABARAP-a; FLJ25768; MGC120154; MGC120155; |
Gene ID : | 11337 |
mRNA Refseq : | NM_007278 |
Protein Refseq : | NP_009209 |
MIM : | 605125 |
UniProt ID : | O95166 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGABARAP contributes to protein aggregation and degradation processes, crucial in maintaining cellular health.
GABARAP impacts GABA receptor trafficking and surface expression, affecting receptor availability and signaling.
GABARAP plays a role in immune cell functioning and modulates inflammatory responses.
GABARAP is involved in autophagy, aiding in the degradation and recycling of cellular components for homeostasis.
GABARAP is linked to the pathology of neurological disorders, potentially affecting protein aggregation and neuronal function.
GABARAP regulates neuronal signaling, particularly at GABAergic synapses, influencing neurotransmission.
Changes in GABARAP expression influence cancer cell behavior, impacting growth, survival, and responsiveness to therapy.
Customer Reviews (3)
Write a reviewPrecise protein quantification, fundamental for our studies' accuracy.
Efficient protein purification, consistent yields, cost-effective service.
Dependable peptide synthesis, accelerates our peptide-based projects.
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