Recombinant Full Length Human GCA Protein, GST-tagged

• Cat.No.: GCA-5164HF
• Product Overview: Human GCA full-length ORF ( AAH05214, 1 a.a. - 217 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 49.61 kDa
• Protein Length: 217 amino acids
• AA Sequence: MAYPGYGGGFGNFSIQVPGMQMGQP VPETGPAILLDGYSGPAYSDTYSSA GDSVYTYFSAVAGQDGEVDAEELQR CLTQSGINGTYSPFSLETCRIMIAM LDRDHTGKMGFNAFKELWAALNAWK ENFMTVDQDGSGTVEHHELRQAIGL MGYRLSPQTLTTIVKRYSKNGRIFF DDYVACCVKLRALTDFFRKRDHLQQ GSANFIYDDFLQGTMAI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GCA grancalcin, EF-hand calcium binding protein [ Homo sapiens ]
• Official Symbol: GCA
• Synonyms: GCA; grancalcin, EF-hand calcium binding protein; grancalcin, EF hand calcium binding protein; grancalcin; GCL; grancalcin, penta-EF-hand protein; grancalcin, EF-hand calcium-binding protein
• Gene ID: 25801
• mRNA Refseq: NM_012198
• Protein Refseq: NP_036330
• MIM: 607030
• UniProt ID: P28676