Recombinant Full Length Human GM2A Protein, C-Flag-tagged
Cat.No. : | GM2A-1665HFL |
Product Overview : | Recombinant Full Length Human GM2A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 20.7 kDa |
AA Sequence : | MQSLMQAPLLIALGLLLAAPAQAHL KKPSQLSSFSWDNCDEGKDPAVIRS LTLEPDPIVVPGNVTLSVVG STSVPLSSPLKVDLVLEKEVAGLWI KIPCTDYIGSCTFEHFCDVLDMLIP TGEPCPEPLRTYGLPCHCPF KEGTYSLPKSEFVVPDLELPSWLTT GNYRIESVLSSSGKRLGCIKIAASL KGITRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Lysosome |
Gene Name : | GM2A ganglioside GM2 activator [ Homo sapiens (human) ] |
Official Symbol : | GM2A |
Synonyms : | GM2AP; SAP-3; GM2-AP |
Gene ID : | 2760 |
mRNA Refseq : | NM_000405.5 |
Protein Refseq : | NP_000396.2 |
MIM : | 613109 |
UniProt ID : | P17900 |
Products Types
◆ Recombinant Protein | ||
GM2A-5001H | Recombinant Human GM2A Protein, GST-tagged | +Inquiry |
GM2A-993H | Recombinant Human GM2A Protein, His (Fc)-Avi-tagged | +Inquiry |
Gm2a-3241M | Recombinant Mouse Gm2a Protein, Myc/DDK-tagged | +Inquiry |
GM2A-299C | Recombinant Cynomolgus Monkey GM2A Protein, His (Fc)-Avi-tagged | +Inquiry |
GM2A-128H | Recombinant Human GM2A Protein (Met1-Ile193), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
GM2A-450HCL | Recombinant Human GM2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket