Recombinant Full Length Human GNAO1 Protein, C-Flag-tagged

• Cat.No.: GNAO1-1523HFL
• Product Overview: Recombinant Full Length Human GNAO1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 39.9 kDa
• AA Sequence: MGCTLSAEERAALERSKAIEKNLKE DGISAAKDVKLLLLGAGESGKSTIV KQMKIIHEDGFSGEDVKQYK PVVYSNTIQSLAAIVRAMDTLGIEY GDKERKADAKMVCDVVSRMEDTEPF SAELLSAMMRLWGDSGIQEC FNRSREYQLNDSAKYYLDSLDRIGA ADYQPTEQDILRTRVKTTGIVETHF TFKNLHFRLFDVGGQRSERK KWIHCFEDVTAIIFCVALSGYDQVL HEDETTNRMHESLKLFDSICNNKWF TDTSIILFLNKKDIFEEKIK KSPLTICFPEYTGPSAFTEAVAYIQ AQYESKNKSAHKEIYTHVTCATDTN NIQFVFDAVTDVIIAKNLRG
  CGLYTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Long-term depression, Melanogenesis

Gene Information

• Gene Name: GNAO1 G protein subunit alpha o1 [ Homo sapiens (human) ]
• Official Symbol: GNAO1
• Synonyms: GNAO; HG1G; DEE17; NEDIM; EIEE17; HLA-DQB1; G-ALPHA-o
• Gene ID: 2775
• mRNA Refseq: NM_138736.3
• Protein Refseq: NP_620073.2
• MIM: 139311
• UniProt ID: P09471