Recombinant Full Length Human GRM7 Protein
Cat.No. : | GRM7-5593HF |
Product Overview : | Human GRM7 full-length ORF (NP_000835.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 102.3 kDa |
Protein Length : | 613 amino acids |
AA Sequence : | MVQLRKLLRVLTLMKFPCCVLEVLL CALAAAARGQEMYAPHSIRIEGDVT LGGLFPVHAKGPSGVPCGDIKRENG IHRLEAMLYALDQINSDPNLLPNVT LGARILDTCSRDTYALEQSLTFVQA LIQKDTSDVRCTNGEPPVFVKPEKV VGVIGASGSSVSIMVANILRLFQIP QISYASTAPELSDDRRYDFFSRVVP PDSFQAQAMVDIVKALGWNYVSTLA SEGSYGEKGVESFTQISKEAGGLCI AQSVRIPQERKDRTIDFDRIIKQLL DTPNSRAVVIFANDEDIKQILAAAK RADQVGHFLWVGSDSWGSKINPLHQ HEDIAEGAITIQPKRATVEGFDAYF TSRTLENNRRNVWFAEYWEENFNCK LTISGSKKEDTDRKCTGQERIGKDS NYEQEGKVQFVIDAVYAMAHALHHM NKDLCADYRGVCPEMEQAGGKKLLK YIRNVNFNGSAGTPVMFNKNGDAPG RYDIFQYQTTNTSNPGYRLIGQWTD ELQLNIEDMQWGKGVREIPASVCTL PCKPGQRKKTQKGTPCCWTCEPCDG YQYQFDEMTCQHCPYDQRPNENRTG CQDIPIIKLEWHSPWAVIPVFLAML GIIATIFVMATFIRYNDTPIVRASG RELSYVLLTGIFLCYIITFLMIAKP DVAVCSFRRVFLGLGMCISYAALLT KTNRIYRIFEQGKKSVTAPRLISPT SQLAITSSLISVQLLGVFIWFGVDP PNIIIDYDEHKTMNPEQARGVLKCD ITDLQIICSLGYSILLMVTCTVYAI KTRGVPENFNEAKPIGFTMYTTCIV WLAFIPIFFGTAQSAEKLYIQTTTL TISMNLSASVALGMLYMPKVYIIIF HPELNVQKRKRSFKAVVTAATMSSR LSHKPSDRPNGEAKTELCENVDPNS PAAKKKYVSYNNLVI |
Applications : | Antibody Production Functional Study Compound Screening |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | GRM7 glutamate receptor, metabotropic 7 [ Homo sapiens ] |
Official Symbol : | GRM7 |
Synonyms : | GRM7; glutamate receptor, metabotropic 7; metabotropic glutamate receptor 7; GLUR7; GPRC1G; mGlu7; MGLUR7; MGLU7; FLJ40498; |
Gene ID : | 2917 |
mRNA Refseq : | NM_000844 |
Protein Refseq : | NP_000835 |
MIM : | 604101 |
UniProt ID : | Q14831 |
Products Types
◆ Recombinant Protein | ||
GRM7-5370H | Recombinant Human GRM7 Protein | +Inquiry |
GRM7-2372R | Recombinant Rat GRM7 Protein, His (Fc)-Avi-tagged | +Inquiry |
GRM7-5371H | Recombinant Human GRM7 Protein, GST-tagged | +Inquiry |
GRM7-3943M | Recombinant Mouse GRM7 Protein, His (Fc)-Avi-tagged | +Inquiry |
GRM7-1144HFL | Recombinant Human GRM7 protein, His&Flag-tagged | +Inquiry |
◆ Lysates | ||
GRM7-5732HCL | Recombinant Human GRM7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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