Recombinant Full Length Human HCLS1 Protein, C-Flag-tagged

• Cat.No.: HCLS1-1979HFL
• Product Overview: Recombinant Full Length Human HCLS1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of transcription, DNA-templated. Located in cytosol; nucleus; and plasma membrane. Part of transcription regulator complex.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 53.8 kDa
• AA Sequence: MWKSVVGHDVSVSVETQGDDWDTDP DFVNDISEKEQRWGAKTIEGSGRTE HINIHQLRNKVSEEHDVLRK KEMESGPKASHGYGGRFGVERDRMD KSAVGHEYVAEVEKHSSQTDAAKGF GGKYGVERDRADKSAVGFDY KGEVEKHTSQKDYSRGFGGRYGVEK DKWDKAALGYDYKGETEKHESQRDY AKGFGGQYGIQKDRVDKSAV GFNEMEAPTTAYKKTTPIEAASSGA RGLKAKFESMAEEKRKREEEEKAQQ VARRQQERKAVTKRSPEAPQ PVIAMEEPAVPAPLPKKISSEAWPP VGTPPSSESEPVRTSREHPVPLLPI RQTLPEDNEEPPALPPRTLE GLQVEEEPVYEAEPEPEPEPEPEPE NDYEDVEEMDRHEQEDEPEGDYEEV LEPEDSSFSSALAGSSGCPA GAGAGAVALGISAVALYDYQGEGSD ELSFDPDDVITDIEMVDEGWWRGRC HGHFGLFPANYVKLLE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors
• Protein Pathways: Pathogenic Escherichia coli infection, Tight junction

Gene Information

• Gene Name: HCLS1 hematopoietic cell-specific Lyn substrate 1 [ Homo sapiens (human) ]
• Official Symbol: HCLS1
• Synonyms: HS1; p75; CTTNL; lckBP1
• Gene ID: 3059
• mRNA Refseq: NM_005335.6
• Protein Refseq: NP_005326.3
• MIM: 601306
• UniProt ID: P14317