Recombinant Full Length Human HDAC1 Protein, C-Flag-tagged
Cat.No. : | HDAC1-1190HFL |
Product Overview : | Recombinant Full Length Human HDAC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 54.9 kDa |
AA Sequence : | MAQTQGTRRKVCYYYDGDVGNYYYG QGHPMKPHRIRMTHNLLLNYGLYRK MEIYRPHKANAEEMTKYHSD DYIKFLRSIRPDNMSEYSKQMQRFN VGEDCPVFDGLFEFCQLSTGGSVAS AVKLNKQQTDIAVNWAGGLH HAKKSEASGFCYVNDIVLAILELLK YHQRVLYIDIDIHHGDGVEEAFYTT DRVMTVSFHKYGEYFPGTGD LRDIGAGKGKYYAVNYPLRDGIDDE SYEAIFKPVMSKVMEMFQPSAVVLQ CGSDSLSGDRLGCFNLTIKG HAKCVEFVKSFNLPMLMLGGGGYTI RNVARCWTYETAVALDTEIPNELPY NDYFEYFGPDFKLHISPSNM TNQNTNEYLEKIKQRLFENLRMLPH APGVQMQAIPEDAIPEESGDEDEDD PDKRISICSSDKRIACEEEF SDSEEEGEGGRKNSSNFKKAKRVKT EDEKEKDPEEKKEVTEEEKTKEEKP EAKGVKEEVKLATRTRPLEQKLISE EDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Adult stem cells, Druggable Genome, Stem cell - Pluripotency, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors |
Protein Pathways : | Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer |
Gene Name : | HDAC1 histone deacetylase 1 [ Homo sapiens (human) ] |
Official Symbol : | HDAC1 |
Synonyms : | HD1; RPD3; KDAC1; GON-10; RPD3L1 |
Gene ID : | 3065 |
mRNA Refseq : | NM_004964.3 |
Protein Refseq : | NP_004955.2 |
MIM : | 601241 |
UniProt ID : | Q13547 |
Products Types
◆ Recombinant Protein | ||
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HDAC1-1052H | Recombinant Human HDAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC1-4088M | Recombinant Mouse HDAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC1-2469R | Recombinant Rat HDAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC1-2855H | Recombinant Human HDAC1 protein(281-480 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
HDAC1-5608HCL | Recombinant Human HDAC1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1737 | HDAC1 Kinetic Assay Kit | +Inquiry |
Kit-2283 | HDAC1 Immunoprecipitation (IP) & Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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