Recombinant Full Length Human HPR Protein, C-Flag-tagged

• Cat.No.: HPR-509HFL
• Product Overview: Recombinant Full Length Human HPR Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 38.8 kDa
• AA Sequence: MSDLGAVISLLLWGRQLFALYSGND VTDISDDRFPKPPEIANGYVEHLFR YQCKNYYRLRTEGDGVYTLN DKKQWINKAVGDKLPECEAVCGKPK NPANPVQRILGGHLDAKGSFPWQAK MVSHHNLTTGATLINEQWLL TTAKNLFLNHSENATAKDIAPTLTL YVGKKQLVEIEKVVLHPNYHQVDIG LIKLKQKVLVNERVMPICLP SKNYAEVGRVGYVSGWGQSDNFKLT DHLKYVMLPVADQYDCITHYEGSTC PKWKAPKSPVGVQPILNEHT FCVGMSKYQEDTCYGDAGSAFAVHD LEEDTWYAAGILSFDKSCAVAEYGV YVKVTSIQHWVQKTIAENTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease, Secreted Protein

Gene Information

• Gene Name: HPR haptoglobin-related protein [ Homo sapiens (human) ]
• Official Symbol: HPR
• Synonyms: HP; A-259H10.2
• Gene ID: 3250
• mRNA Refseq: NM_020995.4
• Protein Refseq: NP_066275.3
• MIM: 140210
• UniProt ID: P00739