Recombinant Full Length Human HSD17B4 Protein, C-Flag-tagged
Cat.No. : | HSD17B4-429HFL |
Product Overview : | Recombinant Full Length Human HSD17B4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 79.5 kDa |
AA Sequence : | MGSPLRFDGRVVLVTGAGAGLGRAY ALAFAERGALVVVNDLGGDFKGVGK GSLAADKVVEEIRRRGGKAV ANYDSVEEGEKVVKTALDAFGRIDV VVNNAGILRDRSFARISDEDWDIIH RVHLRGSFQVTRAAWEHMKK QKYGRIIMTSSASGIYGNFGQANYS AAKLGLLGLANSLAIEGRKSNIHCN TIAPNAGSRMTQTVMPEDLV EALKPEYVAPLVLWLCHESCEENGG LFEVGAGWIGKLRWERTLGAIVRQK NHPMTPEAVKANWKKICDFE NASKPQSIQESTGSIIEVLSKIDSE GGVSANHTSRATSTATSGFAGAIGQ KLPPFSYAYTELEAIMYALG VGASIKDPKDLKFIYEGSSDFSCLP TFGVIIGQKSMMGGGLAEIPGLSIN FAKVLHGEQYLELYKPLPRA GKLKCEAVVADVLDKGSGVVIIMDV YSYSEKELICHNQFSLFLVGSGGFG GKRTSDKVKVAVAIPNRPPD AVLTDTTSLNQAALYRLSGDWNPLH IDPNFASLAGFDKPILHGLCTFGFS ARRVLQQFADNDVSRFKAIK ARFAKPVYPGQTLQTEMWKEGNRIH FQTKVQETGDIVISNAYVDLAPTSG TSAKTPSEGGKLQSTFVFEE IGRRLKDIGPEVVKKVNAVFEWHIT KGGNIGAKWTIDLKSGSGKVYQGPA KGAADTTIILSDEDFMEVVLGKLDP QKAFFSGRLKARGNIMLSQKLQMIL KDYAKL |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Metabolic pathways, Primary bile acid biosynthesis |
Gene Name : | HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 [ Homo sapiens (human) ] |
Official Symbol : | HSD17B4 |
Synonyms : | DBP; MFE-2; MFP-2; MPF-2; PRLTS1; SDR8C1 |
Gene ID : | 3295 |
mRNA Refseq : | NM_000414.4 |
Protein Refseq : | NP_000405.1 |
MIM : | 601860 |
UniProt ID : | P51659 |
Products Types
◆ Recombinant Protein | ||
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Hsd17b4-1180M | Recombinant Mouse Hsd17b4 Protein, MYC/DDK-tagged | +Inquiry |
HSD17B4-4336M | Recombinant Mouse HSD17B4 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSD17B4-2583R | Recombinant Rat HSD17B4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HSD17B4-5373HCL | Recombinant Human HSD17B4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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