Recombinant Full Length Human HSD3B2 Protein, C-Flag-tagged
Cat.No. : | HSD3B2-1441HFL |
Product Overview : | Recombinant Full Length Human HSD3B2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 41.9 kDa |
AA Sequence : | MGWSCLVTGAGGLLGQRIVRLLVEE KELKEIRALDKAFRPELREEFSKLQ NRTKLTVLEGDILDEPFLKR ACQDVSVVIHTACIIDVFGVTHRES IMNVNVKGTQLLLEACVQASVPVFI YTSSIEVAGPNSYKEIIQNG HEEEPLENTWPTPYPYSKKLAEKAV LAANGWNLKNGDTLYTCALRPTYIY GEGGPFLSASINEALNNNGI LSSVGKFSTVNPVYVGNVAWAHILA LRALRDPKKAPSVRGQFYYISDDTP HQSYDNLNYILSKEFGLRLD SRWSLPLTLMYWIGFLLEVVSFLLS PIYSYQPPFNRHTVTLSNSVFTFSY KKAQRDLAYKPLYSWEEAKQ KTVEWVGSLVDRHKETLKSKTQTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Transmembrane |
Protein Pathways : | Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways |
Gene Name : | HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 [ Homo sapiens (human) ] |
Official Symbol : | HSD3B2 |
Synonyms : | HSDB; HSD3B; SDR11E2 |
Gene ID : | 3284 |
mRNA Refseq : | NM_000198.4 |
Protein Refseq : | NP_000189.1 |
MIM : | 613890 |
UniProt ID : | P26439 |
Products Types
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◆ Lysates | ||
HSD3B2-5369HCL | Recombinant Human HSD3B2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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