Recombinant Full Length Human HSP90B1 Protein, C-Flag-tagged

• Cat.No.: HSP90B1-1111HFL
• Product Overview: Recombinant Full Length Human HSP90B1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 90.1 kDa
• AA Sequence: MRALWVLGLCCVLLTFGSVRADDEV DVDGTVEEDLGKSREGSRTDDEVVQ REEEAIQLDGLNASQIRELR EKSEKFAFQAEVNRMMKLIINSLYK NKEIFLRELISNASDALDKIRLISL TDENALSGNEELTVKIKCDK EKNLLHVTDTGVGMTREELVKNLGT IAKSGTSEFLNKMTEAQEDGQSTSE LIGQFGVGFYSAFLVADKVI VTSKHNNDTQHIWESDSNEFSVIAD PRGNTLGRGTTITLVLKEEASDYLE LDTIKNLVKKYSQFINFPIY VWSSKTETVEEPMEEEEAAKEEKEE SDDEAAVEEEEEEKKPKTKKVEKTV WDWELMNDIKPIWQRPSKEV EEDEYKAFYKSFSKESDDPMAYIHF TAEGEVTFKSILFVPTSAPRGLFDE YGSKKSDYIKLYVRRVFITD DFHDMMPKYLNFVKGVVDSDDLPLN VSRETLQQHKLLKVIRKKLVRKTLD MIKKIADDKYNDTFWKEFGT NIKLGVIEDHSNRTRLAKLLRFQSS HHPTDITSLDQYVERMKEKQDKIYF MAGSSRKEAESSPFVERLLK KGYEVIYLTEPVDEYCIQALPEFDG KRFQNVAKEGVKFDESEKTKESREA VEKEFEPLLNWMKDKALKDK IEKAVVSQRLTESPCALVASQYGWS GNMERIMKAQAYQTGKDISTNYYAS QKKTFEINPRHPLIRDMLRR IKEDEDDKTVLDLAVVLFETATLRS GYLLPDTKAYGDRIERMLRLSLNID PDAKVEEEPEEEPEETAEDT
  TEDTEQDEDEEMDVGTDEEEETAKE STAEKDELTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer

Gene Information

• Gene Name: HSP90B1 heat shock protein 90 beta family member 1 [ Homo sapiens (human) ]
• Official Symbol: HSP90B1
• Synonyms: ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m
• Gene ID: 7184
• mRNA Refseq: NM_003299.3
• Protein Refseq: NP_003290.1
• MIM: 191175
• UniProt ID: P14625