Recombinant Full Length Human HSPA6 Protein, C-Flag-tagged

• Cat.No.: HSPA6-1455HFL
• Product Overview: Recombinant Full Length Human HSPA6 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables enzyme binding activity; heat shock protein binding activity; and unfolded protein binding activity. Involved in cellular response to heat and protein refolding. Located in centriole and cytosol. Colocalizes with COP9 signalosome.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 70.8 kDa
• AA Sequence: MQAPRELAVGIDLGTTYSCVGVFQQ GRVEILANDQGNRTTPSYVAFTDTE RLVGDAAKSQAALNPHNTVF DAKRLIGRKFADTTVQSDMKHWPFR VVSEGGKPKVRVCYRGEDKTFYPEE ISSMVLSKMKETAEAYLGQP VKHAVITVPAYFNDSQRQATKDAGA IAGLNVLRIINEPTAAAIAYGLDRR GAGERNVLIFDLGGGTFDVS VLSIDAGVFEVKATAGDTHLGGEDF DNRLVNHFMEEFRRKHGKDLSGNKR ALRRLRTACERAKRTLSSST QATLEIDSLFEGVDFYTSITRARFE ELCSDLFRSTLEPVEKALRDAKLDK AQIHDVVLVGGSTRIPKVQK LLQDFFNGKELNKSINPDEAVAYGA AVQAAVLMGDKCEKVQDLLLLDVAP LSLGLETAGGVMTTLIQRNA TIPTKQTQTFTTYSDNQPGVFIQVY EGERAMTKDNNLLGRFELSGIPPAP RGVPQIEVTFDIDANGILSV TATDRSTGKANKITITNDKGRLSKE EVERMVHEAEQYKAEDEAQRDRVAA KNSLEAHVFHVKGSLQEESL RDKIPEEDRRKMQDKCREVLAWLEH NQLAEKEEYEHQKRELEQICRPIFS RLYGGPGVPGGSSCGTQARQ
  GDPSTGPIIEEVDTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Spliceosome

Gene Information

• Gene Name: HSPA6 heat shock protein family A (Hsp70) member 6 [ Homo sapiens (human) ]
• Official Symbol: HSPA6
• Synonyms: HSP70B'
• Gene ID: 3310
• mRNA Refseq: NM_002155.5
• Protein Refseq: NP_002146.2
• MIM: 140555
• UniProt ID: P17066