Recombinant Full Length Human ICAM1 Protein, C-Flag-tagged

• Cat.No.: ICAM1-1179HFL
• Product Overview: Recombinant Full Length Human ICAM1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.2 kDa
• AA Sequence: MAPSSPRPALPALLVLLGALFPGPG NAQTSVSPSKVILPRGGSVLVTCST SCDQPKLLGIETPLPKKELL LPGNNRKVYELSNVQEDSQPMCYSN CPDGQSTAKTFLTVYWTPERVELAP LPSWQPVGKNLTLRCQVEGG APRANLTVVLLRGEKELKREPAVGE PAEVTTTVLVRRDHHGANFSCRTEL DLRPQGLELFENTSAPYQLQ TFVLPATPPQLVSPRVLEVDTQGTV VCSLDGLFPVSEAQVHLALGDQRLN PTVTYGNDSFSAKASVSVTA EDEGTQRLTCAVILGNQSQETLQTV TIYSFPAPNVILTKPEVSEGTEVTV KCEAHPRAKVTLNGVPAQPL GPRAQLLLKATPEDNGRSFSCSATL EVAGQLIHKNQTRELRVLYGPRLDE RDCPGNWTWPENSQQTPMCQ AWGNPLPELKCLKDGTFPLPIGESV TVTRDLEGTYLCRARSTQGEVTREV TVNVLSPRYEIVIITVVAAA
  VIMGTAGLSTYLYNRQRKIKKYRLQ QAQKGTPMKPNTQATPPTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Viral myocarditis

Gene Information

• Gene Name: ICAM1 intercellular adhesion molecule 1 [ Homo sapiens (human) ]
• Official Symbol: ICAM1
• Synonyms: BB2; CD54; P3.58
• Gene ID: 3383
• mRNA Refseq: NM_000201.3
• Protein Refseq: NP_000192.2
• MIM: 147840
• UniProt ID: P05362