Recombinant Full Length Human ICAM4 Protein, C-Flag-tagged

• Cat.No.: ICAM4-1357HFL
• Product Overview: Recombinant Full Length Human ICAM4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 27.4 kDa
• AA Sequence: MGSLFPLSLLFFLAAAYPGVGSALG RRTKRAQSPKGSPLAPSGTSVPFWV RMSPEFVAVQPGKSVQLNCS NSCPQPQNSSLRTPLRQGKTLRGPG WVSYQLLDVRAWSSLAHCLVTCAGK TRWATSRITAYSVPGGLLGG DPEAWKPGHLFRKPGALHRPGSGQR DLDLRVCCWTPRLLAARDLPRAPQS RRPGGPQQLGTHYTDARLEP
  RAHSFGLRFHRCPCRDPPHCGRCVP MQVPSYEVPGVKGDVLCRLSEKKRN MKQSGEMAIHGGTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein, Transmembrane

Gene Information

• Gene Name: ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) [ Homo sapiens (human) ]
• Official Symbol: ICAM4
• Synonyms: LW; CD242
• Gene ID: 3386
• mRNA Refseq: NM_001039132.3
• Protein Refseq: NP_001034221.1
• MIM: 614088
• UniProt ID: Q14773