Recombinant Full Length Human IDH3A Protein, C-Flag-tagged
Cat.No. : | IDH3A-1349HFL |
Product Overview : | Recombinant Full Length Human IDH3A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 36.6 kDa |
AA Sequence : | MAGPAWISKVSRLLGAFHNPKQVTR GFTGGVQTVTLIPGDGIGPEISAAV MKIFDAAKAPIQWEERNVTA IQGPGGKWMIPSEAKESMDKNKMGL KGPLKTPIAAGHPSMNLLLRKTFDL YANVRPCVSIEGYKTPYTDV NIVTIRENTEGEYSGIEHVIVDGVV QSIKLITEGASKRIAEFAFEYARNN HRSNVTAVHKANIMRMSDGL FLQKCREVAESCKDIKFNEMYLDTV CLNMVQDPSQFDVLVMPNLYGDILS DLCAGLIGGLGVTPSGNIGA NGVAIFESVHGTAPDIAGKDMANPT ALLLSAVMMLRHMGLFDHAARIEAA CFATIKDGKSLTKDLGGNAK CSDFTEEICRRVKDLDTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | Citrate cycle (TCA cycle), Metabolic pathways |
Gene Name : | IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha [ Homo sapiens (human) ] |
Official Symbol : | IDH3A |
Synonyms : | RP90 |
Gene ID : | 3419 |
mRNA Refseq : | NM_005530.3 |
Protein Refseq : | NP_005521.1 |
MIM : | 601149 |
UniProt ID : | P50213 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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