Recombinant Full Length Human ING4 Protein, C-Flag-tagged

• Cat.No.: ING4-1670HFL
• Product Overview: Recombinant Full Length Human ING4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 28.3 kDa
• AA Sequence: MAAGMYLEHYLDSIENLPFELQRNF QLMRDLDQRTEDLKAEIDKLATEYM SSARSLSSEEKLALLKQIQE AYGKCKEFGDDKVQLAMQTYEMVDK HIRRLDTDLARFEADLKEKQIESSD YDSSSSKGKKKGRTQKEKKA ARARSKGKNSDEEAPKTAQKKLKLV RTSPEYGMPSVTFGSVHPSDVLDMP VDPNEPTYCLCHQVSYGEMI
  GCDNPDCSIEWFHFACVGLTTKPRG KWFCPRCSQERKKKTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors

Gene Information

• Gene Name: ING4 inhibitor of growth family member 4 [ Homo sapiens (human) ]
• Official Symbol: ING4
• Synonyms: my036; p29ING4
• Gene ID: 51147
• mRNA Refseq: NM_016162.4
• Protein Refseq: NP_057246.2
• MIM: 608524
• UniProt ID: Q9UNL4