Recombinant Full Length Human IRF3 Protein, C-Flag-tagged
Cat.No. : | IRF3-497HFL |
Product Overview : | Recombinant Full Length Human IRF3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 47 kDa |
AA Sequence : | MGTPKPRILPWLVSQLDLGQLEGVA WVNKSRTRFRIPWKHGLRQDAQQED FGIFQAWAEATGAYVPGRDK PDLPTWKRNFRSALNRKEGLRLAED RSKDPHDPHKIYEFVNSGVGDFSQP DTSPDTNGGGSTSDTQEDIL DELLGNMVLAPLPDPGPPSLAVAPE PCPQPLRSPSLDNPTPFPNLGPSEN PLKRLLVPGEEWEFEVTAFY RGRQVFQQTISCPEGLRLVGSEVGD RTLPGWPVTLPDPGMSLTDRGVMSY VRHVLSCLGGGLALWRAGQW LWAQRLGHCHTYWAVSEELLPNSGH GPDGEVPKDKEGGVFDLGPFIVDLI TFTEGSGRSPRYALWFCVGE SWPQDQPWTKRLVMVKVVPTCLRAL VEMARVGGASSLENTVDLHISNSHP LSLTSDQYKAYLQDLVEGMD FQGPGESTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Transcription Factors |
Protein Pathways : | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway |
Gene Name : | IRF3 interferon regulatory factor 3 [ Homo sapiens (human) ] |
Official Symbol : | IRF3 |
Synonyms : | IIAE7 |
Gene ID : | 3661 |
mRNA Refseq : | NM_001571.6 |
Protein Refseq : | NP_001562.1 |
MIM : | 603734 |
UniProt ID : | Q14653 |
Products Types
◆ Recombinant Protein | ||
IRF3-4603M | Recombinant Mouse IRF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRF3-2146M | Recombinant Mouse IRF3 Protein (1-419 aa), His-Myc-tagged | +Inquiry |
IRF3-072H | Recombinant Human IRF3 Protein, His-tagged | +Inquiry |
IRF3-1196H | Recombinant Human IRF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRF3-013H | Recombinant Human IRF3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IRF3-5166HCL | Recombinant Human IRF3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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