Recombinant Full Length Human IRF4 Protein, C-Flag-tagged
Cat.No. : | IRF4-404HFL |
Product Overview : | Recombinant Full Length Human IRF4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 51.6 kDa |
AA Sequence : | MNLEGGGRGGEFGMSAVSCGNGKLR QWLIDQIDSGKYPGLVWENEEKSIF RIPWKHAGKQDYNREEDAAL FKAWALFKGKFREGIDKPDPPTWKT RLRCALNKSNDFEELVERSQLDISD PYKVYRIVPEGAKKGAKQLT LEDPQMSMSHPYTMTTPYPSLPAQQ VHNYMMPPLDRSWRDYVPDQPHPEI PYQCPMTFGPRGHHWQGPAC ENGCQVTGTFYACAPPESQAPGVPT EPSIRSAEALAFSDCRLHICLYYRE ILVKELTTSSPEGCRISHGH TYDASNLDQVLFPYPEDNGQRKNIE KLLSHLERGVVLWMAPDGLYAKRLC QSRIYWDGPLALCNDRPNKL ERDQTCKLFDTQQFLSELQAFAHHG RSLPRFQVTLCFGEEFPDPQRQRKL ITAHVEPLLARQLYYFAQQN SGHFLRGYDLPEHISNPEDYHRSIR HSSIQETRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Transcription Factors |
Gene Name : | IRF4 interferon regulatory factor 4 [ Homo sapiens (human) ] |
Official Symbol : | IRF4 |
Synonyms : | MUM1; LSIRF; SHEP8; NF-EM5 |
Gene ID : | 3662 |
mRNA Refseq : | NM_002460.4 |
Protein Refseq : | NP_002451.2 |
MIM : | 601900 |
UniProt ID : | Q15306 |
Products Types
◆ Recombinant Protein | ||
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IRF4-2119R | Recombinant Rhesus Macaque IRF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Irf4-3575M | Recombinant Mouse Irf4 Protein, Myc/DDK-tagged | +Inquiry |
IRF4-5039H | Recombinant Human IRF4 Protein, GST-tagged | +Inquiry |
IRF4-2889H | Recombinant Human IRF4 Protein (Glu130-Glu451), N-His tagged | +Inquiry |
◆ Lysates | ||
IRF4-5165HCL | Recombinant Human IRF4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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