Recombinant Full Length Human KAT5 Protein, C-Flag-tagged

• Cat.No.: KAT5-565HFL
• Product Overview: Recombinant Full Length Human KAT5 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 58.4 kDa
• AA Sequence: MAEVGEIIEGCRLPVLRRNQDNEDE WPLAEILSVKDISGRKLFYVHYIDF NKRLDEWVTHERLDLKKIQF PKKEAKTPTKNGLPGSRPGSPEREV PASAQASGKTLPIPVQITLRFNLPK EREAIPGGEPDQPLSSSSCL QPNHRSTKRKVEVVSPATPVPSETA PASVFPQNGAARRAVAAQPGRKRKS NCLGTDEDSQDSSDGIPSAP RMTGSLVSDRSHDDIVTRMKNIECI ELGRHRLKPWYFSPYPQELTTLPVL YLCEFCLKYGRSLKCLQRHL TKCDLRHPPGNEIYRKGTISFFEID GRKNKSYSQNLCLLAKCFLDHKTLY YDTDPFLFYVMTEYDCKGFH IVGYFSKEKESTEDYNVACILTLPP YQRRGYGKLLIEFSYELSKVEGKTG TPEKPLSDLGLLSYRSYWSQ TILEILMGLKSESGERPQITINEIS EITSIKKEDVISTLQYLNLINYYKG QYILTLSEDIVDGHERAMLK
  RLLRIDSKCLHFTPKDWSKRGKWTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors

Gene Information

• Gene Name: KAT5 lysine acetyltransferase 5 [ Homo sapiens (human) ]
• Official Symbol: KAT5
• Synonyms: TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; ZC2HC5; HTATIP1; NEDFASB
• Gene ID: 10524
• mRNA Refseq: NM_006388.4
• Protein Refseq: NP_006379.2
• MIM: 601409
• UniProt ID: Q92993