Recombinant Full Length Human KLK2 Protein, C-Flag-tagged

• Cat.No.: KLK2-239HFL
• Product Overview: Recombinant Full Length Human KLK2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 28.5 kDa
• AA Sequence: MWDLVLSIALSVGCTGAVPLIQSRI VGGWECEKHSQPWQVAVYSHGWAHC GGVLVHPQWVLTAAHCLKKN SQVWLGRHNLFEPEDTGQRVPVSHS FPHPLYNMSLLKHQSLRPDEDSSHD LMLLRLSEPAKITDVVKVLG LPTQEPALGTTCYASGWGSIEPEEF LRPRSLQCVSLHLLSNDMCARAYSE KVTEFMLCAGLWTGGKDTCG
  GDSGGPLVCNGVLQGITSWGPEPCA LPEKPAVYTKVVHYRKWIKDTIAAN PTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease

Gene Information

• Gene Name: KLK2 kallikrein related peptidase 2 [ Homo sapiens (human) ]
• Official Symbol: KLK2
• Synonyms: hK2; hGK-1; KLK2A2
• Gene ID: 3817
• mRNA Refseq: NM_005551.5
• Protein Refseq: NP_005542.1
• MIM: 147960
• UniProt ID: P20151