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Recombinant Full Length Human LTA Protein, C-Flag-tagged

Cat.No. : LTA-2131HFL
Product Overview : Recombinant Full Length Human LTA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
  • Specification
  • Gene Information
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Description : The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 18.6 kDa
AA Sequence : MTPPERLFLPRVRGTTLHLLLLGLL LVLLPGAQGLPGVGLTPSAAQTARQ HPKMHLAHSTLKPAAHLIGD PSKQNSLLWRANTDRAFLQDGFSLS NNSLLVPTSGIYFVYSQVVFSGKAY SPKATSSPLYLAHEVQLFSS QYPFHVPLLSSQKMVYPGLQEPWLH SMYHGAAFQLTQGDQLSTHTDGIPH LVLSPSTVFFGAFAL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways : Antigen processing and presentation, Cytokine-cytokine receptor interaction, Type I diabetes mellitus
Gene Name : LTA lymphotoxin alpha [ Homo sapiens (human) ]
Official Symbol : LTA
Synonyms : LT; TNFB; TNFSF1; TNLG1E
Gene ID : 4049
mRNA Refseq : NM_000595.4
Protein Refseq : NP_000586.2
MIM : 153440
UniProt ID : P01374

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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