Recombinant Full Length Human MAL Protein, C-Flag-tagged

• Cat.No.: MAL-1627HFL
• Product Overview: Recombinant Full Length Human MAL Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 16.5 kDa
• AA Sequence: MAPAAATGGSTLPSGFSVFTTLPDL LFIFEFIFGGLVWILVASSLVPWPL VQGWVMFVSVFCFVATTTLI ILYIIGAHGGETSWVTLDAAYHCTA ALFYLSASVLEALATITMQDGFTYR HYHENIAAVVFSYIATLLYV
  VHAVFSLIRWKSSTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: MAL mal, T cell differentiation protein [ Homo sapiens (human) ]
• Official Symbol: MAL
• Synonyms: MVP17; VIP17
• Gene ID: 4118
• mRNA Refseq: NM_002371.4
• Protein Refseq: NP_002362.1
• MIM: 188860
• UniProt ID: P21145