Recombinant Full Length Human MARVELD2 Protein, C-Flag-tagged

• Cat.No.: MARVELD2-1241HFL
• Product Overview: Recombinant Full Length Human MARVELD2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 64 kDa
• AA Sequence: MSNDGRSRNRDRRYDEVPSDLPYQD TTIRTHPILHDSERAVSADPLPPPP LPLQPPFGPDFYSSDTEEPA IAPDLKPVRRFVPDSWKNFFRGKKK DPEWDKPVSDIRYISDGVECSPPAS PARPNHRSPLNSCKDPYGGS EGTFSSRKEADAVFPRDPYGSLDRH TQTVRTYSEKVEEYNLRYSYMKSWA GLLRILGVVELLLGAGVFAC VTAYIHKDSEWYNLFGYSQPYGMGG VGGLGSMYGGYYYTGPKTPFVLVVA GLAWITTIIILVLGMSMYYR TILLDSNWWPLTEFGINVALFILYM AAAIVYVNDTNRGGLCYYPLFNTPV NAVFCRVEGGQIAAMIFLFV TMIVYLISALVCLKLWRHEAARRHR EYMEQQEINEPSLSSKRKMCEMATS GDRQRDSEVNFKELRTAKMK PELLSGHIPPGHIPKPIVMPDYVAK YPVIQTDDERERYKAVFQDQFSEYK ELSAEVQAVLRKFDELDAVM SRLPHHSESRQEHERISRIHEEFKK KKNDPTFLEKKERCDYLKNKLSHIK QRIQEYDKVMNWDVQGYSTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: MARVELD2 MARVEL domain containing 2 [ Homo sapiens (human) ]
• Official Symbol: MARVELD2
• Synonyms: Tric; DFNB49; MARVD2; MRVLDC2
• Gene ID: 153562
• mRNA Refseq: NM_001038603.3
• Protein Refseq: NP_001033692.2
• MIM: 610572
• UniProt ID: Q8N4S9