Description : |
DNA replication is a carefully orchestrated process involving many proteins that assemble at origins of replication. Among these are the 6 proteins of the minichromosome maintenance (MCM) complex (e.g., MCM2; MIM 116945), which form a hexamer. Each MCM subunit performs an essential function in initiation and elongation of DNA replication. MCMBP can replace MCM2 in the MCM complex, thus forming an alternative MCM hexamer (Sakwe et al., 2007 [PubMed 17296731]). |
Source : |
In Vitro Cell Free System |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
99.1 kDa |
Protein Length : |
640 amino acids |
AA Sequence : |
MPCGEDWLSH PLGIVQGFFA QNGVNPDWEK KVIEYFKEKL KENNAPKWVP SLNEVPLHYL KPNSFVKFRC MIQDMFDPEF YMGVYETVNQ NTKAHVLHFG KYRDVAECGP QQELDLNSPR NTTLERQTFY CVPVPGESTW VKEAYVNANQ ARVSPSTSYT PSRHKRSYED DDDMDLQPNK QKDQHAGARQ AGSVGGLQWC GEPKRLETEA STGQQLNSLN LSSPFDLNFP LPGEKGPACL VKVYEDWDCF KVNDILELYG ILSVDPVLSI LNNDERDASA LLDPMECTDT AEEQRVHSPP ASLVPRIHVI LAQKLQHINP LLPACLNKEE SKTFVSSFMS ELSPVRAELL GFLTHALLGD SLAAEYLILH LISTVYTRRD VLPLGKFTVN LSGCPRNSTF TEHLYRIIQH LVPASFRLQM TIENMNHLKF IPHKDYTANR LVSGLLQLPS NTSLVIDETL LEQGQLDTPG VHNVTALSNL ITWQKVDYDF SYHQMEFPCN INVFITSEGR SLLPADCQIH LQPQLIPPNM EEYMNSLLSA VLPSVLNKFR IYLTLLRFLE YSISDEITKA VEDDFVEMRK NDPQSITADD LHQLLVVARC LSLSAGQTTL SRERWLRAKQ LESLRRTRLQ QQKCVNGNEL |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |