Recombinant Full Length Human MDH2 Protein, C-Flag-tagged

• Cat.No.: MDH2-1619HFL
• Product Overview: Recombinant Full Length Human MDH2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 35.3 kDa
• AA Sequence: MLSALARPVSAALRRSFSTSAQNNA KVAVLGASGGIGQPLSLLLKNSPLV SRLTLYDIAHTPGVAADLSH IETKAAVKGYLGPEQLPDCLKGCDV VVIPAGVPRKPGMTRDDLFNTNATI VATLTAACAQHCPEAMICVI ANPVNSTIPITAEVFKKHGVYNPNK IFGVTTLDIVRANTFVAELKGLDPA RVNVPVIGGHAGKTIIPLIS QCTPKVDFPQDQLTALTGRIQEAGT EVVKAKAGAGSATLSMAYAGARFVF SLVDAMNGKEGVVECSFVKS
  QETECTYFSTPLLLGKKGIEKNLGI GKVSSFEEKMISDAIPELKASIKKG EDFVKTLKTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Pyruvate metabolism

Gene Information

• Gene Name: MDH2 malate dehydrogenase 2 [ Homo sapiens (human) ]
• Official Symbol: MDH2
• Synonyms: MDH; MOR1; DEE51; M-MDH; EIEE51; MGC:3559
• Gene ID: 4191
• mRNA Refseq: NM_005918.4
• Protein Refseq: NP_005909.2
• MIM: 154100
• UniProt ID: P40926