Recombinant Full Length Human MPO Protein, C-Flag-tagged
Cat.No. : | MPO-1300HFL |
Product Overview : | Recombinant Full Length Human MPO Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 83.7 kDa |
AA Sequence : | MGVPFFSSLRCMVDLGPCWAGGLTA EMKLLLALAGLLAILATPQPSEGAA PAVLGEVDTSLVLSSMEEAK QLVDKAYKERRESIKQRLRSGSASP MELLSYFKQPVAATRTAVRAADYLH VALDLLERKLRSLWRRPFNV TDVLTPAQLNVLSKSSGCAYQDVGV TCPEQDKYRTITGMCNNRRSPTLGA SNRAFVRWLPAEYEDGFSLP YGWTPGVKRNGFPVALARAVSNEIV RFPTDQLTPDQERSLMFMQWGQLLD HDLDFTPEPAARASFVTGVN CETSCVQQPPCFPLKIPPNDPRIKN QADCIPFFRSCPACPGSNITIRNQI NALTSFVDASMVYGSEEPLA RNLRNMSNQLGLLAVNQRFQDNGRA LLPFDNLHDDPCLLTNRSARIPCFL AGDTRSSEMPELTSMHTLLL REHNRLATELKSLNPRWDGERLYQE ARKIVGAMVQIITYRDYLPLVLGPT AMRKYLPTYRSYNDSVDPRI ANVFTNAFRYGHTLIQPFMFRLDNR YQPMEPNPRVPLSRVFFASWRVVLE GGIDPILRGLMATPAKLNRQ NQIAVDEIRERLFEQVMRIGLDLPA LNMQRSRDHGLPGYNAWRRFCGLPQ PETVGQLGTVLRNLKLARKL MEQYGTPNNIDIWMGGVSEPLKRKG RVGPLLACIIGTQFRKLRDGDRFWW ENEGVFSMQQRQALAQISLP RIICDNTGITTVSKNNIFMSNSYPR DFVNCSTLPALNLASWREASTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | MPO myeloperoxidase [ Homo sapiens (human) ] |
Official Symbol : | MPO |
Synonyms : | Myeloperoxidase |
Gene ID : | 4353 |
mRNA Refseq : | NM_000250.2 |
Protein Refseq : | NP_000241.1 |
MIM : | 606989 |
UniProt ID : | P05164 |
Products Types
◆ Recombinant Protein | ||
Mpo-1790R | Recombinant Rat Mpo Protein, His-tagged | +Inquiry |
MPO-2943H | Recombinant Human MPO Protein, GST-tagged | +Inquiry |
MPO-5506H | Recombinant Human MPO Protein, GST-tagged | +Inquiry |
MPO-527H | Recombinant Human MPO Protein (Met1-Ser745), His-tagged | +Inquiry |
MPO-51H | Recombinant Human MPO Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
MPO-01H | Active Native Human MPO Protein | +Inquiry |
MPO -27H | Active Native Human Myeloperoxidase | +Inquiry |
MPO-8220H | Native Human Neutrophil Myeloperoxidase | +Inquiry |
◆ Lysates | ||
MPO-4234HCL | Recombinant Human MPO 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0607 | Myeloperoxidase Peroxidation Fluorometric Assay Kit | +Inquiry |
Kit-0604 | MPO Inhibitor Screening Assay Kit | +Inquiry |
Kit-0606 | Myeloperoxidase Chlorination Fluorometric Assay Kit | +Inquiry |
Kit-1986 | Neutrophil Myeloperoxidase Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMPO is synthesized and stored by granulocytes in the bone marrow.
MPO mediates the production of halogenated oxidants in phagosomes and plays a key role in bacterial killing and protecting the body from disease.
Under physiological conditions in the body, MPO catalyzes the production of hypochlorous acid.
MPO can be used as a marker for cerebral stroke.
MPO has been associated with studies of diseases such as leukemia and coronary heart disease.
Customer Reviews (3)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The MPO proteins purchased from your company is suitable for WB.
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