Recombinant Full Length Human MPST Protein

• Cat.No.: MPST-311HF
• Product Overview: Recombinant full length Human MPST (amino acids 1-297) with N terminal proprietary tag, 58.74 kDa.

Specification

• Description: This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 58.740kDa inclusive of tags
• Protein Length: 297 amino acids
• AA Sequence: MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPK LGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAE HFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAF GHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDP AFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGI EPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL SKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWY MRARPEDVISEGRGKTH
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: MPST mercaptopyruvate sulfurtransferase [ Homo sapiens (human) ]
• Official Symbol: MPST
• Synonyms: MPST; mercaptopyruvate sulfurtransferase; 3-mercaptopyruvate sulfurtransferase; human liver rhodanese; MST; TST2
• Gene ID: 4357
• mRNA Refseq: NM_001013436
• Protein Refseq: NP_001013454
• MIM: 602496
• UniProt ID: P25325