Recombinant Full Length Human MTHFR Protein, C-Flag-tagged
Cat.No. : | MTHFR-1253HFL |
Product Overview : | Recombinant Full Length Human MTHFR Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 74.4 kDa |
AA Sequence : | MVNEARGNSSLNPCLEGSASSGSES SKDSSRCSTPGLDPERHERLREKMR RRLESGDKWFSLEFFPPRTA EGAVNLISRFDRMAAGGPLYIDVTW HPAGDPGSDKETSSMMIASTAVNYC GLETILHMTCCRQRLEEITG HLHKAKQLGLKNIMALRGDPIGDQW EEEEGGFNYAVDLVKHIRSEFGDYF DICVAGYPKGHPEAGSFEAD LKHLKEKVSAGADFIITQLFFEADT FFRFVKACTDMGITCPIVPGIFPIQ GYHSLRQLVKLSKLEVPQEI KDVIEPIKDNDAAIRNYGIELAVSL CQELLASGLVPGLHFYTLNREMATT EVLKRLGMWTEDPRRPLPWA LSAHPKRREEDVRPIFWASRPKSYI YRTQEWDEFPNGRWGNSSSPAFGEL KDYYLFYLKSKSPKEELLKM WGEELTSEASVFEVFVLYLSGEPNR NGHKVTCLPWNDEPLAAETSLLKEE LLRVNRQGILTINSQPNING KPSSDPIVGWGPSGGYVFQKAYLEF FTSRETAEALLQVLKKYELRVNYHL VNVKGENITNAPELQPNAVT WGIFPGREIIQPTVVDPVSFMFWKD EAFALWIEQWGKLYEEESPSRTIIQ YIHDNYFLVNLVDNDFPLDN CLWQVVEDTLELLNRPTQNARETEA PTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Metabolic pathways, Methane metabolism, One carbon pool by folate |
Gene Name : | MTHFR methylenetetrahydrofolate reductase [ Homo sapiens (human) ] |
Official Symbol : | MTHFR |
Synonyms : | 5,10-methylenetetrahydrofolate reductase (NADPH); methylenetetrahydrofolate reductase intermediate form; OTTHUMP00000002367; OTTHUMP00000002368 |
Gene ID : | 4524 |
mRNA Refseq : | NM_005957.5 |
Protein Refseq : | NP_005948.3 |
MIM : | 607093 |
UniProt ID : | P42898 |
Products Types
◆ Recombinant Protein | ||
MTHFR-1454H | Recombinant Human MTHFR Protein, His (Fc)-Avi-tagged | +Inquiry |
MTHFR-1465H | Recombinant Human MTHFR Protein (1-656 aa), His-tagged | +Inquiry |
Mthfr-4212M | Recombinant Mouse Mthfr Protein, Myc/DDK-tagged | +Inquiry |
MTHFR-459C | Recombinant Cynomolgus Monkey MTHFR Protein, His (Fc)-Avi-tagged | +Inquiry |
MTHFR-670H | Recombinant Human MTHFR Protein (1-656 aa), His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
MTHFR-4081HCL | Recombinant Human MTHFR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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