| Description : |
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
81.550kDa inclusive of tags |
| Protein Length : |
504 amino acids |
| AA Sequence : |
MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKA NDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSST QRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRE LGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLR QENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSR EVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGE GDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPY TQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPR PLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEI PGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGA IVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVS SYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYN PLEKKLFAWDNLNMVTYDIKLSKM |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
