Recombinant Full Length Human NLN Protein, C-Flag-tagged

• Cat.No.: NLN-1282HFL
• Product Overview: Recombinant Full Length Human NLN Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 80.5 kDa
• AA Sequence: MIARCLLAVRSLRRVGGSRILLRMT LGREVMSPLQAMSSYTVAGRNVLRW DLSPEQIKTRTEELIVQTKQ VYDAVGMLGIEEVTYENCLQALADV EVKYIVERTMLDFPQHVSSDKEVRA ASTEADKRLSRFDIEMSMRG DIFERIVHLQETCDLGKIKPEARRY LEKSIKMGKRNGLHLPEQVQNEIKS MKKRMSELCIDFNKNLNEDD TFLVFSKAELGALPDDFIDSLEKTD DDKYKITLKYPHYFPVMKKCCIPET RRRMEMAFNTRCKEENTIIL QQLLPLRTKVAKLLGYSTHADFVLE MNTAKSTSRVTAFLDDLSQKLKPLG EAEREFILNLKKKECKDRGF EYDGKINAWDLYYYMTQTEELKYSI DQEFLKEYFPIEVVTEGLLNTYQEL LGLSFEQMTDAHVWNKSVTL YTVKDKATGEVLGQFYLDLYPREGK YNHAACFGLQPGCLLPDGSRMMAVA ALVVNFSQPVAGRPSLLRHD EVRTYFHEFGHVMHQICAQTDFARF SGTNVETDFVEVPSQMLENWVWDVD SLRRLSKHYKDGSPIADDLL EKLVASRLVNTGLLTLRQIVLSKVD QSLHTNTSLDAASEYAKYCSEILGV AATPGTNMPATFGHLAGGYD GQYYGYLWSEVFSMDMFYSCFKKEG IMNPEVGMKYRNLILKPGGSLDGMD MLHNFLKREPNQKAFLMSRG
  LHAPTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Renin-angiotensin system

Gene Information

• Gene Name: NLN neurolysin [ Homo sapiens (human) ]
• Official Symbol: NLN
• Synonyms: MEP; MOP; AGTBP; EP24.16
• Gene ID: 57486
• mRNA Refseq: NM_020726.5
• Protein Refseq: NP_065777.1
• MIM: 611530
• UniProt ID: Q9BYT8