Recombinant Full Length Human NME7 Protein, GST-tagged

• Cat.No.: NME7-7011HF
• Product Overview: Recombinant Human full-length NME7(1 a.a. - 376 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Description: This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 68.9 kDa
• Protein Length: 376 amino acids
• AA Sequence: MNHSERFVFIAEWYDPNASLLRRYE LLFYPGDGSVEMHDVKNHRTFLKRT KYDNLHLEDLFIGNKVNVFSRQLVL IDYGDQYTARQLGSRKEKTLALIKP DAISKAGEIIEIINKAGFTITKLKM MMLSRKEALDFHVDHQSRPFFNELI QFITTGPIIAMEILRDDAICEWKRL LGPANSGVARTDASESIRALFGTDG IRNAAHGPDSFASAAREMELFFPSS GGCGPANTAKFTNCTCCIVKPHAVS EGLLGKILMAIRDAGFEISAMQMFN MDRVNVEEFYEVYKGVVTEYHDMVT EMYSGPCVAMEIQQNNATKTFREFC GPADPEIARHLRPGTLRAIFGKTKI QNAVHCTDLPEDGLLEVQYFFKILD N
• Applications: ELISA; WB-Re; AP; Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NME7 NME/NM23 family member 7 [ Homo sapiens (human) ]
• Official Symbol: NME7
• Synonyms: NME7; NME/NM23 family member 7; non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase); EC 2.7.4.6; FLJ37194; MN23H7; NDK 7; nucleoside diphosphate kinase 7; NDP kinase 7; nucleoside-diphosphate kinase 7; nm23-H7; OTTHUMP00000032536; OTTHUMP00000231077; OTTHUMP00000231078
• Gene ID: 29922
• mRNA Refseq: NM_013330
• Protein Refseq: NP_037462
• MIM: 613465
• UniProt ID: Q9Y5B8