Recombinant Full Length Human OSBP Protein, C-Flag-tagged

• Cat.No.: OSBP-774HFL
• Product Overview: Recombinant Full Length Human OSBP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 89.2 kDa
• AA Sequence: MAATELRGVVGPGPAAIAALGGGGA GPPVVGGGGGRGDAGPGSGAASGTV VAAAAGGPGPGAGGVAAAGP APAPPTGGSGGSGAGGSGSAREGWL FKWTNYIKGYQRRWFVLSNGLLSYY RSKAEMRHTCRGTINLATAN ITVEDSCNFIISNGGAQTYHLKASS EVERQRWVTALELAKAKAVKMLAES DESGDEESVSQTDKTELQNT LRTLSSKVEDLSTCNDLIAKHGTAL QRSLSELESLKLPAESNEKIKQVNE RATLFRITSNAMINACRDFL MLAQTHSKKWQKSLQYERDQRIRLE ETLEQLAKQHNHLERAFRGATVLPA NTPGNVGSGKDQCCSGKGDM SDEDDENEFFDAPEIITMPENLGHK RTGSNISGASSDISLDEQYKHQLEE TKKEKRTRIPYKPNYSLNLW SIMKNCIGKELSKIPMPVNFNEPLS MLQRLTEDLEYHELLDRAAKCENSL EQLCYVAAFTVSSYSTTVFR TSKPFNPLLGETFELDRLEENGYRS LCEQVSHHPPAAAHHAESKNGWTLR QEIKITSKFRGKYLSIMPLG TIHCIFHATGHHYTWKKVTTTVHNI IVGKLWIDQSGEIDIVNHKTGDKCN LKFVPYSYFSRDVARKVTGE VTDPSGKVHFALLGTWDEKMECFKV QPVIGENGGDARQRGHEAEESRVML WKRNPLPKNAENMYYFSELA LTLNAWESGTAPTDSRLRPDQRLME NGRWDEANAEKQRLEEKQRLSRKKR EAEAMKATEDGTPYDPYKAL
  WFERKKDPVTKELTHIYRGEYWECK EKQDWSSCPDIFTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: OSBP oxysterol binding protein [ Homo sapiens (human) ]
• Official Symbol: OSBP
• Synonyms: OSBP1
• Gene ID: 5007
• mRNA Refseq: NM_002556.3
• Protein Refseq: NP_002547.1
• MIM: 167040
• UniProt ID: P22059