Recombinant Full Length Human OTUD5 Protein, C-Flag-tagged
Cat.No. : | OTUD5-2009HFL |
Product Overview : | Recombinant Full Length Human OTUD5 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 60.4 kDa |
AA Sequence : | MTILPKKKPPPPDADPANEPPPPGP MPPAPRRGGGVGVGGGGTGVGGGDR DRDSGVVGARPRASPPPQGP LPGPPGALHRWALAVPPGAVAGPRP QQASPPPCGGPGGPGGGPGDALGAA AAGVGAAGVVVGVGGAVGVG GCCSGPGHSKRRRQAPGVGAVGGGS PEREEVGAGYNSEDEYEAAAARIEA MDPATVEQQEHWFEKALRDK KGFIIKQMKEDGACLFRAVADQVYG DQDMHEVVRKHCMDYLMKNADYFSN YVTEDFTTYINRKRKNNCHG NHIEMQAMAEMYNRPVEVYQYSTGT SAVEPINTFHGIHQNEDEPIRVSYH RNIHYNSVVNPNKATIGVGL GLPSFKPGFAEQSLMKNAIKTSEES WIEQQMLEDKKRATDWEATNEAIEE QVARESYLQWLRDQEKQARQ VRGPSQPRKASATCSSATAAASSGL EEWTSRSPRQRSSASSPEHPELHAE LGMKPPSPGTVLALAKPPSP CAPGTSSQFSAGADRATSPLVSLYP ALECRALIQQMSPSAFGLNDWDDDE ILASVLAVSQQEYLDSMKKN KVHRDPPPDKS TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Protease |
Protein Pathways : | RIG-I-like receptor signaling pathway |
Gene Name : | OTUD5 OTU deubiquitinase 5 [ Homo sapiens (human) ] |
Official Symbol : | OTUD5 |
Synonyms : | DUBA; MCAND |
Gene ID : | 55593 |
mRNA Refseq : | NM_017602.4 |
Protein Refseq : | NP_060072.1 |
MIM : | 300713 |
UniProt ID : | Q96G74 |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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