Recombinant Full Length Human PCBP4 Protein, C-Flag-tagged

• Cat.No.: PCBP4-2001HFL
• Product Overview: Recombinant Full Length Human PCBP4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.3 kDa
• AA Sequence: MSGSDGGLEEEPELSITLTLRMLMH GKEVGSIIGKKGETVKRIREQSSAR ITISEGSCPERITTITGSTA AVFHAVSMIAFKLDEDLCAAPANGG NVSRPPVTLRLVIPASQCGSLIGKA GTKIKEIRETTGAQVQVAGD LLPNSTERAVTVSGVPDAIILCVRQ ICAVILESPPKGATIPYHPSLSLGT VLLSANQGFSVQGQYGAVTP AEVTKLQQLSSHAVPFATPSVVPGL DPGTQTSSQEFLVPNDLIGCVIGRQ GSKISEIRQMSGAHIKIGNQ AEGAGERHVTITGSPVSIALAQYLI TACLETAKSTSGGTPSSAPADLPAP FSPPLTALPTAPPGLLGTPY AISLSNFIGLKPMPFLALPPASPGP PPGLAAYTAKMAAANGSKKAERQKF SPY TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: PCBP4 poly(rC) binding protein 4 [ Homo sapiens (human) ]
• Official Symbol: PCBP4
• Synonyms: CBP; LIP4; MCG10
• Gene ID: 57060
• mRNA Refseq: NM_033008.3
• Protein Refseq: NP_127501.1
• MIM: 608503
• UniProt ID: P57723