| Description : |
The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
84.410kDa inclusive of tags |
| Protein Length : |
530 amino acids |
| AA Sequence : |
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKK ANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTP HTFPHSRYMSQMSVPEQAELEKLKQRINFSDLDQRSIGSD SQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTSP PNRETIGSAQCKELFASALSNDLLQNCQVSEEDGRGEPAM ESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLT HLIDHLKEQEKSYMKFLKKILARENEEEDVRTIDSAVGSG SVAESTSLNIDVQSEASDTTARDPQQEPMEEIENLKKQHD LLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSV VAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPAV PDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMR VLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRST SAPSASVGLAPVVNGESNSLTSSVPYPTASLVSQNESENE GHLNPSEKLQ |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
