Recombinant Full Length Human PDK4 Protein

• Cat.No.: PDK4-369HF
• Product Overview: Recombinant full length Human PDK4 with proprietary tag; Predicted MWt 71.32 kDa.

Specification

• Description: This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 71.320kDa inclusive of tags
• Protein Length: 411 amino acids
• AA Sequence: MKAARFVLRSAGSLNGAGLVPREVE HFSRYSPSPLSMKQLLDFGSENACE RTSFAFLRQELPVRLANILKEIDIL PTQLVNTSSVQLVKSWYIQSLMDLV EFHEKSPDDQKALSDFVDTLIKVRN RHHNVVPTMAQGIIEYKDACTVDPV TNQNLQYFLDRFYMNRISTRMLMNQ HILIFSDSQTGNPSHIGSIDPNCDV VAVVQDAFECSRMLCDQYYLSSPEL KLTQVNGKFPDQPIHIVYVPSHLHH MLFELFKNAMRATVEHQENQPSLTP IEVIVVLGKEDLTIKISDRGGGVPL RIIDRLFSYTYSTAPTPVMDNSRNA PLAGFGYGLPISRLYAKYFQGDLNL YSLSGYGTDAIIYLKALSSESIEKL PVFNKSAFKHYQMSSEADDWCIPSR EPKNLAKEVAM
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: PDK4 pyruvate dehydrogenase kinase, isozyme 4 [ Homo sapiens ]
• Official Symbol: PDK4
• Synonyms: PDK4; pyruvate dehydrogenase kinase, isozyme 4; pyruvate dehydrogenase kinase, isoenzyme 4
• Gene ID: 5166
• mRNA Refseq: NM_002612
• Protein Refseq: NP_002603
• MIM: 602527
• UniProt ID: Q16654