Recombinant Full Length Human PDLIM5 Protein, C-Flag-tagged

• Cat.No.: PDLIM5-1606HFL
• Product Overview: Recombinant Full Length Human PDLIM5 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 63.8 kDa
• AA Sequence: MSNYSVSLVGPAPWGFRLQGGKDFN MPLTISSLKDGGKAAQANVRIGDVV LSIDGINAQGMTHLEAQNKI KGCTGSLNMTLQRASAAPKPEPVPV QKGEPKEVVKPVPITSPAVSKVTST NNMAYNKAPRPFGSVSSPKV TSIPSPSSAFTPAHATTSSHASPSP VAAVTPPLFAASGLHANANLSADQS PSALSAGKTAVNVPRQPTVT SVCSETSQELAEGQRRGSQGDSKQQ NGPPRKHIVERYTEFYHVPTHSDAS KKRLIEDTEDWRPRTGTTQS RSFRILAQITGTEHLKESEADNTKK ANNSQEPSPQLASSVASTRSMPESL DSPTSGRPGVTSLTTAAAFK PVGSTGVIKSPSWQRPNQGVPSTGR ISNSAAYSGSVAPANSALGQTQPSD QDTLVQRAEHIPAGKRTPMC AHCNQVIRGPFLVALGKSWHPEEFN CAHCKNTMAYIGFVEEKGALYCELC YEKFFAPECGRCQRKILGEV INALKQTWHVSCFVCVACGKPIRNN VFHLEDGEPYCETDYYALFGTICHG CEFPIEAGDMFLEALGYTWH
  DTCFVCSVCCESLEGQTFFSKKDKP LCKKHAHSVNFTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: PDLIM5 PDZ and LIM domain 5 [ Homo sapiens (human) ]
• Official Symbol: PDLIM5
• Synonyms: L9; ENH; LIM; ENH1
• Gene ID: 10611
• mRNA Refseq: NM_006457.5
• Protein Refseq: NP_006448.5
• MIM: 605904
• UniProt ID: Q96HC4